Calpain5 expression is decreased in endometriosis and regulated by HOXA10 in human endometrial cells
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چکیده
منابع مشابه
Calpain5 expression is decreased in endometriosis and regulated by HOXA10 in human endometrial cells.
Calpains have been implicated in the regulation of apoptosis. Here, we identified Calpain5 as a target of HOXA10 transcriptional regulation in endometrial cells as well as its aberrant regulation in endometriosis. Histologically confirmed biopsies of endometriosis were obtained from 20 women. Eutopic endometrium was collected by endometrial biopsy from 30 controls and from the 20 subjects with ...
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متن کاملAltered expression of HOXA10 in endometriosis: potential role in decidualization.
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متن کاملO-31: Epigenetic Aberration of HOXA10 Gene in Human Endometrium throughout The Menstrual Cycle in Endometriosis
Background: Epigenetic aberration such as DNA methylation and histone modifications appear to be involved in various diseases such as Endometriosis. Here, we investigated the epigenetic regulation of HOXA10 promoter, as a crucial gene, responsible for uterine organogenesis, functional endometrial differentiation and endometrial receptivity, and its correlation with mRNA expression of this gene ...
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ژورنال
عنوان ژورنال: Molecular Human Reproduction
سال: 2008
ISSN: 1360-9947,1460-2407
DOI: 10.1093/molehr/gan055